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She Was Labeled the Original ‘Anti-Vaxxer,’ Now She Feels VindicatedJenny McCarthy (C) at her son Evan’s high school graduation with her husband, Donnie Wahlberg, in an undated photo. McCarthy says Evan’s condition improved after she discovered Generation Rescue, a nonprofit that promotes a protocol to help autistic children. Courtesy of Jenny McCarthy Productions

Twenty years have passed since Jenny McCarthy became a household name as the original “anti-vaxxer”—a label she has always rejected.

Her journey from an actress to a figurehead of autism advocacy began when her 2½-year-old son was diagnosed with the condition after receiving the MMR vaccine. At the time, the Centers for Disease Control and Prevention’s (CDC) stated position was unequivocal: The vaccine did not cause autism.
Fast forward to November 2025 and discussion about autism is mainstream; propelled by Health Secretary Robert F. Kennedy Jr.’s pledge to determine the cause of the condition, which now impacts 1 in 31 children in the United States, according to the CDC.
The CDC has also dropped the definitive position that vaccines do not cause autism—a shift in position that many medics disagree with.

For McCarthy, it is a moment of vindication and of answered prayers.

“A lot still needs to happen,” she told The Epoch Times. “But at least we’re on a path now where children can have a better chance of not having this happen to them, and generations can be saved from the pain that we have gone through as parents.”

McCarthy, 53, rose to the spotlight as a model, actress, and television host in the 1990s, but became a household name in 2005 after she shared the story of her son Evan’s autism diagnosis.

Along with campaigning for autism awareness, McCarthy did not shy away from her belief that the MMR vaccine had been part of the cause, quickly earning her the anti-vaxxer label.

“As far as I know, I was the first public figure to have that label, even though I have always said I’m not against vaccines, but I’m for vaccine safety,” she said.

From Entertainer to Campaigner

McCarthy’s unexpected path from entertainer to campaigner began a few days before Evan’s MMR shot, when she read a Time magazine feature about parents who said their children developed symptoms of autism after receiving the vaccine.

“I felt a pit in my stomach, perhaps mother’s intuition, that Evan should not get this shot,” McCarthy said. Then, McCarthy was married to film director John Asher, who was also at the appointment.

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Jenny McCarthy is embraced by her then-husband, actor John Asher, at the 57th Golden Globe Awards in Beverly Hills, Calif., on Jan. 23, 2000. McCarthy, 53, became a household name in 2005 after she shared the story of her son Evan’s autism diagnosis after he got the MMR vaccine. Vinnie Zuffante/Getty Images

McCarthy expressed her concerns to the pediatrician and referenced the article. She asked if he could hold off on the vaccine.

“He got very angry at me and said it was just parents’ desperate attempts to blame something. He said the vaccine had nothing to do with it,” McCarthy said.

She refused to sign a waiver allowing the physician to administer the MMR vaccine. Asher signed it, and Evan received the shot.

That is when life for son and mother abruptly changed.

“Until that point, he had hit every milestone that a child his age should reach. After the MMR shot, he started showing regression. His babbling stopped. Eye contact went away. He no longer smiled,” McCarthy said.

“He developed blue circles under his eyes, a bloated belly, gas, constipation, eczema, yeast,” she added. “I didn’t know then that these are all comorbid conditions that go with autism. I didn’t know why Evan was suddenly unhealthy and sick.”

McCarthy does not believe that the MMR shot alone triggered Evan’s autism. She blames “a compilation of so many shots to a kid who clearly had autoimmune disorders.”

Still, Evan’s most serious reaction occurred after the MMR vaccine.

The same year, McCarthy was drinking her coffee one morning when she sensed something was wrong. She walked into Evan’s bedroom and found him struggling to breathe.

“He was shaking, and he had pasty white and blue lips,” she said.

Frantic, she called 911, and it took the paramedics around 20 minutes to stop what they said was a febrile seizure.

Three weeks later, Evan was struggling to breathe again. By the time paramedics arrived, he had gone into cardiac arrest. They administered CPR, brought Evan back, lost him again, then brought him back while in the ambulance, McCarthy recalled.

Doctors diagnosed him with epilepsy and gave him anti-seizure medication.

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A vial of MMR vaccine is prepared at a pediatric office in Coral Gables, Fla., on Sept. 12, 2025. Health Secretary Robert F. Kennedy Jr. has pledged to determine the cause of autism, which affects 1 in 31 U.S. children, according to the Centers for Disease Control and Prevention. Joe Raedle/Getty Images

“They kept asking me if anyone in the family has a history of epilepsy. Nobody did. The mommy instinct in me told me there was something more to the story,” she said.

After visits to multiple physicians, a neurologist diagnosed Evan with autism.

“He just said, ‘I’m sorry, he has autism, and there’s not a lot you can do. There’s some therapies, behavior therapies, but I’m sorry,’” McCarthy said.

“I felt helpless. I left that office devastated, hopeless, and cried in my bed.”

First Eye Contact

That night, McCarthy opened Google and searched for the condition. In the sponsored links, she discovered Generation Rescue, a nonprofit that provided assistance to families affected by autism spectrum disorders. The ad said, “Autism is reversible.”

McCarthy initially doubted the organization’s credibility.

“Remember, at this time, there was little information online about autism. And if it was true, why didn’t one of the best neurologists in the world tell me there’s something I could do to reverse autism?” McCarthy said.

Generation Rescue suggested a protocol that included the removal of gluten and casein from the child’s diet. McCarthy called her pediatrician and asked his opinion. He discouraged her, but she decided to give it a try anyway.

Within two weeks of removing wheat and dairy from Evan’s diet, he had more direct eye contact and had increased his language.

She followed the next step and added vitamins and supplements. His sleeping and overall behavior improved.

“It was like someone turned the light switch back on. Words started coming out of his mouth again,” McCarthy said. “If I didn’t click on Generation Rescue’s website, I never would have found how to help heal Evan. I followed the path of all these other moms, and I felt it was my calling to use my platform to help parents who were feeling so helpless.”

Generation Rescue was founded by J.B. Handley, an autism advocate who has written two books on the condition: “How To End the Autism Epidemic” and “Underestimated: An Autism Miracle,” in which Handley and his son, Jamison, tell the story of the latter’s journey to find a method of communication that allowed him to emerge from his self-described “prison of silence.”
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Jenny McCarthy and her son, Evan Asher, in an undated photo. Evan was diagnosed with autism at a young age after suffering several medical emergencies. Courtesy of Jenny McCarthy Productions

The book inspired the 2023 documentary “Spellers,” which chronicles the lives of eight children who are nonverbal with autism.

Handley commends McCarthy for her passion and courage to use her platform to educate parents, knowing that she would face backlash that could harm her professional career.

“Our mission had always been to warn and educate as many parents as humanly possible,” Handley told The Epoch Times. “If we were bumping along, going a mile an hour, trying to get the word out, Jenny took us up 200 miles an hour overnight.”

“She told the truth at great expense to her,” he added.

In 2007, McCarthy appeared on “Oprah” to promote her book “Louder Than Words: A Mother’s Journey in Healing Autism.” She told her story in detail and initially the response was favorable.

“I literally had thousands of messages from parents who thanked me, because finally there was someone reaffirming they were not crazy. Even Oprah said they had been waiting for years for someone to come on and tell their story about this topic,” McCarthy recalled.

Launch of ‘Anti-Vax’ Label

Not long after, McCarthy encountered pushback from critics who don’t believe vaccines are tied to autism.

One day, a man knocked on the door and asked to speak with her.

“He told me that he runs a public relations company and was approached by a government agency that wanted to hire him to create a campaign against me labeling me as an anti-vaxxer,” McCarthy said.

“That was the first time I had heard that term. I kinda laughed and said, ‘Well, that’s not gonna stick because in every media appearance I make it clear that I’m not against vaccines, I’m for making them safer and looking at the ingredients and side effects,’” she added.

The man told McCarthy that he declined the agency’s offer because he also had a son with autism.

“He told me they would hire another agency to create the campaign against me, but I didn’t give it a second thought,” she said.

“I was naive. In a matter of a few months, bullets began flying my way. Suddenly, I was no longer known as an actress, an author, a mother, or a wife. I was just an anti-vaxxer. That was my title for a very long time,” she said.

The backlash impacted McCarthy’s professional career. She said she lost several endorsement deals.

She wrote books “to keep a roof over [her] head” and spent several years traveling the country as a keynote speaker at autism conventions and talking to parents of children with autism in phone consultations.

The CDC Reversal

The CDC now states that it’s possible vaccines cause autism, a reversal of the long-standing stance that dated back to before McCarthy’s son was vaccinated.

“The claim ‘vaccines do not cause autism’ is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autismIn,” the CDC states in a Nov. 19 update on its website.

“Studies supporting a link have been ignored by health authorities.”

A Health and Human Services-led investigation includes evaluating “plausible biologic mechanisms between early childhood vaccinations and autism,” the CDC said.

The CDC previously said that “studies have shown that there is no link between receiving vaccines and developing autism spectrum disorder” and that no links have been found between any vaccine ingredients and the disorder.

Some autism campaign groups and medical organizations have criticized the shift in stance.

The Autism Science Foundation issued a statement on Nov. 20 claiming the CDC’s page about autism is “now filled with anti-vaccine rhetoric and outright lies about vaccines and autism.”
Dr. Susan Kressly, president of the American Academy of Pediatrics, issued a statement the same day, saying the conclusion that there is no link between vaccines and autism is “clear and unambiguous.”
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Jenny McCarthy (C), her husband Donnie Wahlberg, and her son Evan Asher in an undated photo. Courtesy of Jenny McCarthy Productions

Naturally, McCarthy applauds Kennedy’s efforts as health secretary.

“I’ve never prayed so hard in my life for Bobby Kennedy to be doing what he’s doing,” she said.

“I’m still not anti-vaccine,” she added. “I want safe ones. Show us the safety trials, and then we’ll talk.”

McCarthy said she would like some vaccines to be removed from the childhood schedule, such as the hepatitis vaccines. She also believes triple shots, such as the MMR vaccine, should be separated into individual shots and that safety trials should be conducted.

Melissa Renee, a mother of four, received news in 2005 that her oldest son had autism and her oldest daughter had Asperger’s syndrome, a previously used diagnosis on the autism spectrum, according to Autism Speaks.

The diagnoses were made after the children each received the DPT vaccine for diphtheria, pertussis, and tetanus.

“I had no idea what to do. I felt like I was isolated on an island with no one to help,” Renee told The Epoch Times.

Renee also discovered Generation Rescue online, and she followed the protocol the organization recommended, as McCarthy had done.

She used glutathione and plant enzymes, removed gluten and casein, cut out artificial dyes, and implemented chelation therapy, which removes toxic metals from the body, among other actions.

“They rapidly improved in a short time. I never gave them the MMR vaccine because of what I learned from listening to Jenny,” Renee said.

Renee lived in Mississippi when her children were diagnosed. She said she felt empowered by McCarthy’s advocacy and became involved in advocacy herself, pushing for vaccine exemptions and championing informed consent, children’s rights, and parents’ rights related to medical freedom.

A former allopathic medical professional, Renee is now a holistic health practitioner who will become a board certified naturopathic physician next year. She specializes in treating children with autism and other neurobehavioral disorders.

“[McCarthy] was called crazy. Every one of us who followed her were labeled with a derogatory term using her last name,” Renee recalled.

“She risked everything at a time when so many of us felt alone. She was so influential and gave all of us confidence to speak up and have our own voice.”

A Story of Recovery and Pride

Today, Evan is 23. He graduated from high school and college. He still takes Lamictal, an anti-seizure medication, and it has been several years since his last seizure.

McCarthy, who is now married to actor and former New Kids on the Block band member Donnie Wahlberg, is a judge on “The Masked Singer.” Evan is a production assistant on the show. He also has a YouTube channel, and in 2023, recorded his first song, “It Doesn’t Matter.”
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Homesteader Melissa Renee teaches a foraging class at the Heritage Explorers Fest and History Fair in McArthur, Ohio, on Oct. 16, 2025. Following McCarthy’s path, Renee also discovered the nonprofit Generation Rescue after her son was diagnosed with autism. Jeff Louderback/The Epoch Times

“People ask me if I cured Evan. I didn’t. There is no cure for autism as far as I know. What I did was recover him from autism,” said McCarthy.

She said she looks at the condition through the lens of injury.

“You can go in and fix the parts that are injured—like the immune system, like the gut,” she said.

Evan told The Epoch Times that it’s a “huge sense of relief” that the topic of autism has reached the mainstream, and that Kennedy, the HHS, and the Make America Healthy Again movement are addressing the condition.

“Younger generations are being diagnosed earlier. The more we understand, the more support they’ll have as they grow. As time goes on and life changes, this knowledge is going to help future generations even more,” he said.

Evan praised his mother for all she has done.

“I want people to see how hard she has fought for me and how far I’ve come. And I want people to know you can still fully be yourself if you have autism,” he said.

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